Leptin increases mitotic index and regeneration ratio in hepatectomized rats

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Leptin increases mitotic index and regeneration ratio in hepatectomized rats

BACKGROUND The aim of this study was to evaluate the potential effect of intraperitoneal administration of leptin on the hepatic regeneration and the mitotic index. MATERIAL AND METHODS 56 Sprague-Dawley rats were divided into 7 groups each containing 8 rats. Group 1 was evaluated as the sham group and no surgical procedure was performed on animals. The rats in groups 2, 3, and 4 (named C24, ...

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Effect of cyclosporine on liver regeneration in partial hepatectomized rats.

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Preparation of Partially Hepatectomized Rats

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Hepatic Branch Vagotomy Can Suppress Liver Regeneration in Partially Hepatectomized Rats

The role of the vagus nerve in liver regeneration after partial hepatectomy was studied by comparing the effects of hepatic branch vagotomy with those of hepatic branch sympathectomy in rats. The liver weight as a percentage of body weight decreased significantly 7 days after vagotomy compared with the controls and this was associated with a reduction in food intake. There was no difference in ...

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Human liver stem cell-derived microvesicles accelerate hepatic regeneration in hepatectomized rats

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ژورنال

عنوان ژورنال: Medical Science Monitor Basic Research

سال: 2013

ISSN: 2325-4416

DOI: 10.12659/msmbr.889591